Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 15 entries
Sorted by: Best Match Show Resources per page
Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine.

The open pain journal

Iadarola MJ, Gonnella GL.
PMID: 26779292
Open Pain J. 2013;6:95-107. doi: 10.2174/1876386301306010095. Epub 2013 Mar 08.

This review examines existing preclinical and clinical studies related to resiniferatoxin (RTX) and its potential uses in pain treatment. Like capsaicin, RTX is a vanilloid receptor (TRPV1) agonist, only more potent. This increased potency confers both quantitative and qualitative...

Cite
Iadarola MJ, Gonnella GL. Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine. Open Pain J. 2013;6:95-107doi: 10.2174/1876386301306010095.
Iadarola, M. J., & Gonnella, G. L. (2013). Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine. The open pain journal, 695-107. https://doi.org/10.2174/1876386301306010095
Iadarola, Michael J, and Gonnella, Gian Luigi. "Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine." The open pain journal vol. 6 (2013): 95-107. doi: https://doi.org/10.2174/1876386301306010095
Iadarola MJ, Gonnella GL. Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine. Open Pain J. 2013;6:95-107. doi: 10.2174/1876386301306010095. Epub 2013 Mar 08. PMID: 26779292; PMCID: PMC4711370.
Copy Download .nbib Format: NLM
c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?.

The open pain journal

Gao YJ, Ji RR.
PMID: 19898681
Open Pain J. 2009 Jan 01;2:11-17. doi: 10.2174/1876386300902010011.

c-Fos, the protein of the protooncogene c-fos, has been extensively used as a marker for the activation of nociceptive neurons in the spinal cord for more than twenty years since Hunt et al. first reported that peripheral noxious stimulation...

Cite
Gao YJ, Ji RR. c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?. Open Pain J. 2009;2:11-17doi: 10.2174/1876386300902010011.
Gao, Y. J., & Ji, R. R. (2009). c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?. The open pain journal, 211-17. https://doi.org/10.2174/1876386300902010011
Gao, Yong-Jing, and Ji, Ru-Rong. "c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?." The open pain journal vol. 2 (2009): 11-17. doi: https://doi.org/10.2174/1876386300902010011
Gao YJ, Ji RR. c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury?. Open Pain J. 2009 Jan 01;2:11-17. doi: 10.2174/1876386300902010011. PMID: 19898681; PMCID: PMC2773551.
Copy Download .nbib Format: NLM
Targeting TRPV3 for the Development of Novel Analgesics.

The open pain journal

Huang SM, Chung MK.
PMID: 25285178
Open Pain J. 2013;6:119-126. doi: 10.2174/1876386301306010119.

Decades of characterization of the transient receptor potential vanilloid subtype 1 (TRPV1) has led to the realization of its central role in thermosensation and pain perception. A large number of pharmaceutical companies have had interest in developing TPRV1 antagonists...

Cite
Huang SM, Chung MK. Targeting TRPV3 for the Development of Novel Analgesics. Open Pain J. 2013;6:119-126doi: 10.2174/1876386301306010119.
Huang, S. M., & Chung, M. K. (2013). Targeting TRPV3 for the Development of Novel Analgesics. The open pain journal, 6119-126. https://doi.org/10.2174/1876386301306010119
Huang, Susan M, and Chung, Man-Kyo. "Targeting TRPV3 for the Development of Novel Analgesics." The open pain journal vol. 6 (2013): 119-126. doi: https://doi.org/10.2174/1876386301306010119
Huang SM, Chung MK. Targeting TRPV3 for the Development of Novel Analgesics. Open Pain J. 2013;6:119-126. doi: 10.2174/1876386301306010119. PMID: 25285178; PMCID: PMC4182939.
Copy Download .nbib Format: NLM
The Role of Suggestions in Hypnosis for Chronic Pain: A Review of the Literature.

The open pain journal

Dillworth T, Jensen MP.
PMID: 21686037
Open Pain J. 2010;3(1):39-51. doi: 10.2174/1876386301003010039.

Several controlled trials have demonstrated that hypnosis is an efficacious treatment for chronic pain. However, less attention has been given to the specific procedures and suggestions used in hypnotic treatments in research. The goal of this review was to...

Cite
Dillworth T, Jensen MP. The Role of Suggestions in Hypnosis for Chronic Pain: A Review of the Literature. Open Pain J. 2010;3(1):39-51doi: 10.2174/1876386301003010039.
Dillworth, T., & Jensen, M. P. (2010). The Role of Suggestions in Hypnosis for Chronic Pain: A Review of the Literature. The open pain journal, 3(1), 39-51. https://doi.org/10.2174/1876386301003010039
Dillworth, Tiara, and Jensen, Mark P. "The Role of Suggestions in Hypnosis for Chronic Pain: A Review of the Literature." The open pain journal vol. 3,1 (2010): 39-51. doi: https://doi.org/10.2174/1876386301003010039
Dillworth T, Jensen MP. The Role of Suggestions in Hypnosis for Chronic Pain: A Review of the Literature. Open Pain J. 2010;3(1):39-51. doi: 10.2174/1876386301003010039. PMID: 21686037; PMCID: PMC3113537.
Copy Download .nbib Format: NLM
Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats.

The open pain journal

Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G.
PMID: 20559459
Open Pain J. 2009;2:30-40. doi: 10.2174/1876386300902010030.

Injection of endothelin-1 (ET-1) into the plantar rat hindpaw causes acute pain at high concentrations and tactile sensitization at low concentrations. The pro-nociceptive actions are driven through ET(A) receptors for both levels of [ET-1], but the ET(B) receptors are...

Cite
Khodorova A, Zou S, Ren K, et al. Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. Open Pain J. 2009;2:30-40doi: 10.2174/1876386300902010030.
Khodorova, A., Zou, S., Ren, K., Dubner, R., Davar, G., & Strichartz, G. (2009). Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. The open pain journal, 230-40. https://doi.org/10.2174/1876386300902010030
Khodorova, Alla, et al. "Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats." The open pain journal vol. 2 (2009): 30-40. doi: https://doi.org/10.2174/1876386300902010030
Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G. Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. Open Pain J. 2009;2:30-40. doi: 10.2174/1876386300902010030. PMID: 20559459; PMCID: PMC2886510.
Copy Download .nbib Format: NLM
Neuron, Glia and Reciprocal Relationships in Pain Processing.

The open pain journal

Ren K.
PMID: 21179400
Open Pain J. 2009 Jan 01;2:7-31. doi: 10.2174/1876386301003010001.

No abstract available.

Cite
Ren K. Neuron, Glia and Reciprocal Relationships in Pain Processing. Open Pain J. 2009;2:7-31doi: 10.2174/1876386301003010001.
Ren, K. (2009). Neuron, Glia and Reciprocal Relationships in Pain Processing. The open pain journal, 27-31. https://doi.org/10.2174/1876386301003010001
Ren, Ke. "Neuron, Glia and Reciprocal Relationships in Pain Processing." The open pain journal vol. 2 (2009): 7-31. doi: https://doi.org/10.2174/1876386301003010001
Ren K. Neuron, Glia and Reciprocal Relationships in Pain Processing. Open Pain J. 2009 Jan 01;2:7-31. doi: 10.2174/1876386301003010001. PMID: 21179400; PMCID: PMC3004479.
Copy Download .nbib Format: NLM
Therapeutic potential of RNA interference in pain medicine.

The open pain journal

Tan PH, Yang LC, Ji RR.
PMID: 19966919
Open Pain J. 2009 Jan 01;2:57-63. doi: 10.2174/1876386300902010057.

In recent years RNA interference (RNAi) has rapidly become the most widely used tool for gene knockdown due to its high specificity and potency. RNAi is an evolutionarily conserved mechanism for silencing gene expression by targeted degradation of mRNA....

Cite
Tan PH, Yang LC, Ji RR. Therapeutic potential of RNA interference in pain medicine. Open Pain J. 2009;2:57-63doi: 10.2174/1876386300902010057.
Tan, P. H., Yang, L. C., & Ji, R. R. (2009). Therapeutic potential of RNA interference in pain medicine. The open pain journal, 257-63. https://doi.org/10.2174/1876386300902010057
Tan, Ping-Heng, et al. "Therapeutic potential of RNA interference in pain medicine." The open pain journal vol. 2 (2009): 57-63. doi: https://doi.org/10.2174/1876386300902010057
Tan PH, Yang LC, Ji RR. Therapeutic potential of RNA interference in pain medicine. Open Pain J. 2009 Jan 01;2:57-63. doi: 10.2174/1876386300902010057. PMID: 19966919; PMCID: PMC2788313.
Copy Download .nbib Format: NLM
The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain.

The open pain journal

Chi-Fei Wang J, Hung CH, Gerner P, Ji RR, Strichartz GR.
PMID: 24567767
Open Pain J. 2013;6:190-198. doi: 10.2174/1876386301306010190.

Thoracotomy often results in chronic pain, characterized by resting pain and elevated mechano-sensitivity. This paper defines complex behavioral responses to tactile stimulation in rats after thoracotomy, shown to be reversibly relieved by systemic morphine, in order to develop a...

Cite
Chi-Fei Wang J, Hung CH, Gerner P, et al. The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain. Open Pain J. 2013;6:190-198doi: 10.2174/1876386301306010190.
Chi-Fei Wang, J., Hung, C. H., Gerner, P., Ji, R. R., & Strichartz, G. R. (2013). The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain. The open pain journal, 6190-198. https://doi.org/10.2174/1876386301306010190
Chi-Fei Wang, Jeffrey, et al. "The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain." The open pain journal vol. 6 (2013): 190-198. doi: https://doi.org/10.2174/1876386301306010190
Chi-Fei Wang J, Hung CH, Gerner P, Ji RR, Strichartz GR. The Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain. Open Pain J. 2013;6:190-198. doi: 10.2174/1876386301306010190. PMID: 24567767; PMCID: PMC3932053.
Copy Download .nbib Format: NLM
Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons.

The open pain journal

Liu BG, Dobretsov M, Stimers JR, Zhang JM.
PMID: 20165558
Open Pain J. 2008 Jan 01;1:1. doi: 10.2174/1876386300801010001.

Tumor necrosis factor-α (TNF-α), a pro-inflammatory cytokine, produces pain and hyperalgesia by activating and/or sensitizing nociceptive sensory neurons. In the present study, using whole-cell patch clamp techniques, the regulation of potassium currents by TNF-α was examined in acutely dissociated...

Cite
Liu BG, Dobretsov M, Stimers JR, et al. Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. Open Pain J. 2008;1:1doi: 10.2174/1876386300801010001.
Liu, B. G., Dobretsov, M., Stimers, J. R., & Zhang, J. M. (2008). Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. The open pain journal, 11. https://doi.org/10.2174/1876386300801010001
Liu, Bao-Gang, et al. "Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons." The open pain journal vol. 1 (2008): 1. doi: https://doi.org/10.2174/1876386300801010001
Liu BG, Dobretsov M, Stimers JR, Zhang JM. Tumor Necrosis Factor-α Suppresses Activation of Sustained Potassium Currents in Rat Small Diameter Sensory Neurons. Open Pain J. 2008 Jan 01;1:1. doi: 10.2174/1876386300801010001. PMID: 20165558; PMCID: PMC2822358.
Copy Download .nbib Format: NLM
Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice.

The open pain journal

Hanstein R, Zhao JB, Basak R, Smith DN, Zuckerman YY, Hanani M, Spray DC, Gulinello M.
PMID: 21151805
Open Pain J. 2010 Jan 01;3:123-133. doi: 10.2174/1876386301003010123.

A focal and transitory inflammation induced by injection of complete Freund's adjuvant (CFA) in the submandibular skin of mice elicits pain behavior that persists for several weeks after the initial inflammation has resolved. Chronic pain, assessed as tactile hypersensitivity...

Cite
Hanstein R, Zhao JB, Basak R, et al. Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice. Open Pain J. 2010;3:123-133doi: 10.2174/1876386301003010123.
Hanstein, R., Zhao, J. B., Basak, R., Smith, D. N., Zuckerman, Y. Y., Hanani, M., Spray, D. C., & Gulinello, M. (2010). Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice. The open pain journal, 3123-133. https://doi.org/10.2174/1876386301003010123
Hanstein, Regina, et al. "Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice." The open pain journal vol. 3 (2010): 123-133. doi: https://doi.org/10.2174/1876386301003010123
Hanstein R, Zhao JB, Basak R, Smith DN, Zuckerman YY, Hanani M, Spray DC, Gulinello M. Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice. Open Pain J. 2010 Jan 01;3:123-133. doi: 10.2174/1876386301003010123. PMID: 21151805; PMCID: PMC2999631.
Copy Download .nbib Format: NLM
A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet.

The open pain journal

Clinkinbeard T, Kline RH, Zhang LP, McIlwrath SL, Watkins JF, Westlund KN.
PMID: 34326907
Open Pain J. 2017;10(1):81-89. doi: 10.2174/1876386301710010081. Epub 2017 Sep 15.

BACKGROUND/AIMS: Study of acute pancreatitis in chemically-induced rodent models has provided useful data; models of alcoholic chronic pancreatitis have not been available in mice. The aim of the present study was to characterize a mouse model of chronic pancreatitis...

Cite
Clinkinbeard T, Kline RH, Zhang LP, et al. A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet. Open Pain J. 2017;10(1):81-89doi: 10.2174/1876386301710010081.
Clinkinbeard, T., Kline, R. H., Zhang, L. P., McIlwrath, S. L., Watkins, J. F., & Westlund, K. N. (2017). A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet. The open pain journal, 10(1), 81-89. https://doi.org/10.2174/1876386301710010081
Clinkinbeard, T, et al. "A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet." The open pain journal vol. 10,1 (2017): 81-89. doi: https://doi.org/10.2174/1876386301710010081
Clinkinbeard T, Kline RH, Zhang LP, McIlwrath SL, Watkins JF, Westlund KN. A Mouse Model of Chronic Pancreatitis Induced by an Alcohol and High Fat Diet. Open Pain J. 2017;10(1):81-89. doi: 10.2174/1876386301710010081. Epub 2017 Sep 15. PMID: 34326907; PMCID: PMC8317824.
Copy Download .nbib Format: NLM
Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry.

The open pain journal

Shimizu K, Chai B, Lagraize SC, Wei F, Dubner R, Ren K.
PMID: 20221418
Open Pain J. 2009 Jan 01;2:76-83. doi: 10.2174/1876386300902010076.

Our recent studies indicate that the prototypic proinflammatory cytokine IL-1β is upregulated in astroglial cells in the trigeminal interplolaris/caudalis (Vi/Vc) transition zone, a region of the spinal trigeminal complex involved in trigeminal pain processing, after masseter muscle inflammation. Here...

Cite
Shimizu K, Chai B, Lagraize SC, et al. Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry. Open Pain J. 2009;2:76-83doi: 10.2174/1876386300902010076.
Shimizu, K., Chai, B., Lagraize, S. C., Wei, F., Dubner, R., & Ren, K. (2009). Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry. The open pain journal, 276-83. https://doi.org/10.2174/1876386300902010076
Shimizu, K, et al. "Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry." The open pain journal vol. 2 (2009): 76-83. doi: https://doi.org/10.2174/1876386300902010076
Shimizu K, Chai B, Lagraize SC, Wei F, Dubner R, Ren K. Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry. Open Pain J. 2009 Jan 01;2:76-83. doi: 10.2174/1876386300902010076. PMID: 20221418; PMCID: PMC2835306.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 15 entries